INT182924

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.90
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RARA, NR1H4) signal transduction (RARA, NR1H4) nucleus (RARA, NR1H4)
enzyme binding (RARA) transcription factor binding (RARA) cytoplasm (RARA)
RARA (Homo sapiens)
NR1H4 (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 26 96.32 Very High Very High Very High
Rheumatoid Arthritis 92 90.48 High High
Breast Cancer 76 76.48 Quite High
Apoptosis 96 50.00 Quite Low
Repression 8 14.20 Low Low
Disease 24 5.00 Very Low Very Low Very Low
Neuroblastoma 12 5.00 Very Low Very Low Very Low
Advanced Or Metastatic Breast Cancer 10 5.00 Very Low Very Low Very Low
Toxicity 10 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This situation is similar to that found with the RXR/RAR heterodimer bound to a DR1 (43), or the RXR/VDR heterodimer bound to a DR5 (44), which cannot trigger transcriptional activation through these elements.
RAR Binding (heterodimer) of RXR
1) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0 Pain Relevance 0
This situation is similar to that found with the RXR/RAR heterodimer bound to a DR1 (43), or the RXR/VDR heterodimer bound to a DR5 (44), which cannot trigger transcriptional activation through these elements.
RAR Binding (heterodimer) of RXR
2) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0 Pain Relevance 0
Following stimulation by retinoids, RAR-RXR heterodimers and RXR-RXR homodimers can form [23-25].
RAR Binding (heterodimers) of RXR
3) Confidence 0.01 Published 2010 Journal Breast Cancer Res Section Body Doc Link PMC2949655 Disease Relevance 0.95 Pain Relevance 0
Following stimulation by retinoids, RAR-RXR heterodimers and RXR-RXR homodimers can form [23-25].
RAR Binding (heterodimers) of RXR
4) Confidence 0.01 Published 2010 Journal Breast Cancer Res Section Body Doc Link PMC2949655 Disease Relevance 0.95 Pain Relevance 0

General Comments

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