INT182929

Context Info Confidence 0.18 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 3 Disease Relevance 0.37 Pain Relevance 0.19

signal transduction (CREB1, KCNIP3) nucleus (CREB1, KCNIP3) nucleoplasm (CREB1) mitochondrion (CREB1) Golgi apparatus (KCNIP3) endoplasmic reticulum (KCNIP3)

CREB1 (Homo sapiens) KCNIP3 (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 3 63.36 antagonist 6 45.12

Disease Link Frequency Relevance Heat Pain 3 63.36 Neuroblastoma 18 60.80 Rheumatoid Arthritis 60 5.00 Repression 12 5.00 Apoptosis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, in the absence of Ca2+, DREAM binds to LCDs located in the KID domain of cAMP response element-binding protein (CREB).

cAMP response element-binding protein Binding (binds) of DREAM

1) Confidence 0.18 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.12 Pain Relevance 0.06

In addition, in the absence of Ca2+, DREAM binds to LCDs located in the KID domain of cAMP response element-binding protein (CREB).

cAMP response element-binding protein Binding (binds) of DREAM

2) Confidence 0.18 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.12 Pain Relevance 0.06

In addition, in the absence of Ca2+, DREAM binds to LCDs located in the KID domain of cAMP response element-binding protein (CREB).

CREB Binding (binds) of DREAM

3) Confidence 0.18 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.12 Pain Relevance 0.06

General Comments

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