INT182945

From wiki-pain
Revision as of 21:40, 20 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TNFRSF25, KCNIP3) signal transduction (TNFRSF25, KCNIP3) plasma membrane (TNFRSF25, KCNIP3)
Golgi apparatus (KCNIP3) endoplasmic reticulum (KCNIP3) DNA binding (KCNIP3)
TNFRSF25 (Homo sapiens)
KCNIP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 60 88.24 High High
Repression 12 15.12 Low Low
Neuroblastoma 18 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Association of DREAM to both the DRE and the DR3 was competed with an excess of either unlabeled oligonucleotide, whereas a non-related competitor did not affect retardation (Figure 1B).
DR3 Binding (Association) of DREAM
1) Confidence 0.23 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.08 Pain Relevance 0
As shown in Figure 1A, recombinant DREAM bound to the DR3 with a stronger affinity than to the consensus DRE of the prodynorphin gene (compare lanes 3 and 6).
DR3 Binding (bound) of DREAM
2) Confidence 0.20 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.09 Pain Relevance 0
However, as shown in Figure 7A, the receptors and DREAM appear to bind independently to the DR3 or DR5 elements, since neither the formation of larger complexes by occupancy of the same DNA molecule nor the appearance of complexes with intermediate mobilities due to the interaction of DREAM with the receptors was detected.
DR3 Binding (bind) of DREAM
3) Confidence 0.18 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox