INT183895

Context Info Confidence 0.01 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.37 Pain Relevance 0

intracellular (CAV1, Racgap1) cytoplasm (CAV1, Racgap1) cell differentiation (Racgap1) transport (Racgap1) mitochondrion (CAV1) embryo development (Racgap1)

Anatomy Link Frequency arm 2 CAV1 (Homo sapiens) Racgap1 (Mus musculus)

Pain Link Frequency Relevance Heat Chronic pancreatitis 2 5.00 Inflammation 2 5.00 fibrosis 1 5.00

Disease Link Frequency Relevance Heat Cancer 31 86.96 Adenocarcinoma 51 71.96 Pancreatic Cancer 7 50.00 Metastasis 23 25.52 Carcinoma 1 9.84 Pancreatitis 2 5.00 Inflammatory Breast Neoplasms 2 5.00 Renal Cancer 1 5.00 Pressure And Volume Under Development 1 5.00 Targeted Disruption 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These data further suggest that activation of RhoC GTPase is regulated by cav-1 and that RhoC signals through the p38 arm of the MAPK pathway to induce cellular migration.

cav-1 Regulation (regulated) of Positive_regulation (activation) of GTPase in arm

1) Confidence 0.01 Published 2005 Journal Mol Cancer Section Body Doc Link PMC1173138 Disease Relevance 0.37 Pain Relevance 0

General Comments

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