INT184046

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Context Info
Confidence 0.32
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Stat6) nucleus (Stat6) DNA binding (Stat6)
cytoplasm (Stat6) signal transducer activity (Stat6)
Stat6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 50 50.00 Quite Low
Inflammation 34 22.52 Low Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 11 93.12 High High
Diabetes Mellitus 2 85.76 High High
Obesity 3 85.24 High High
Metabolic Disorder 1 84.60 Quite High
Insulin Resistance 3 78.72 Quite High
Necrosis 2 71.36 Quite High
Cancer 13 71.00 Quite High
Weight Gain 1 58.56 Quite High
Body Weight 2 49.00 Quite Low
Paresis 1 25.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This interaction of SOCS5 with the IL-4 receptor is likely to cause the reduction in IL-4-induced activation of STAT6 and thus to regulate Th2 polarization.
Positive_regulation (induced) of Positive_regulation (activation) of STAT6
1) Confidence 0.32 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.92 Pain Relevance 0

General Comments

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