INT18422

Context Info Confidence 0.45 First Reported 1989 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 6 Total Number 6 Disease Relevance 1.71 Pain Relevance 1.22

peptidase activity (Plg) extracellular space (Plg) extracellular region (Plg)

Anatomy Link Frequency blood 1 leukocytes 1 Plg (Rattus norvegicus)

Pain Link Frequency Relevance Heat Inflammation 5 100.00 Angina 9 94.20 cINOD 3 89.92 anesthesia 1 80.88 Inflammatory response 1 25.00

Disease Link Frequency Relevance Heat INFLAMMATION 9 100.00 Coagulation Disorder 1 98.08 Cv General 3 Under Development 5 94.20 Angina 4 90.40 Myocardial Infarction 2 85.76 Coronary Artery Disease 2 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Role of plasminogen activators and leukocytes in IUD-induced inflammation: effect of some anti-inflammatory agents.

Regulation (effect) of plasminogen in leukocytes associated with inflammation

1) Confidence 0.45 Published 1989 Journal Adv Contracept Section Title Doc Link 2517376 Disease Relevance 0.65 Pain Relevance 0.48

The aim of the study was to assess the effect of cardiothoracic surgery on the dynamics of plasminogen, D-dimers and plasminogen activator inhibitor (PAI-I) during the first 24 h after surgery.

Regulation (effect) of plasminogen

2) Confidence 0.07 Published 2005 Journal Clin. Chem. Lab. Med. Section Abstract Doc Link 15653441 Disease Relevance 0 Pain Relevance 0.08

The mean activity values of the tissue activator inhibitor plasminogen and C-protein, the levels of plasminogen, antithrombin III, and fibrinogen remained unchanged.

Regulation (values) of plasminogen

3) Confidence 0.03 Published 1993 Journal Kardiologiia Section Abstract Doc Link 8377358 Disease Relevance 0.22 Pain Relevance 0.07

Absence of significant changes in plasminogen level may be an indicator of the nonenzymic route of fibrinogen system activation.

Regulation (changes) of plasminogen

4) Confidence 0.02 Published 1990 Journal Sov Med Section Abstract Doc Link 1973307 Disease Relevance 0.33 Pain Relevance 0.24

A generalized fibrinolytic state was produced in both groups as evidenced by a fall in fibrinogen and plasminogen levels, prolongation of thrombin and reptilase clotting times, a rise in fibrinogen degradation products, and a shortening of the euglobulin lysis time.

Regulation (fall) of plasminogen associated with coagulation disorder

5) Confidence 0.01 Published 1990 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 2301285 Disease Relevance 0.26 Pain Relevance 0.09

Lp(a), fibrinogen, plasminogen, PAI-1 and t-PA levels were measured and C-reactive protein (CRP) assays were performed on admission for all patients, and venous blood samples were drawn 12 and 24 h later for cTn-I measurements.

Regulation (measured) of plasminogen in blood

6) Confidence 0.01 Published 2005 Journal Int. J. Clin. Pract. Section Abstract Doc Link 15854189 Disease Relevance 0.25 Pain Relevance 0.25

General Comments

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