INT184459

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adamts1) extracellular region (Adamts1) proteinaceous extracellular matrix (Adamts1)
Anatomy Link Frequency
nasal cartilage 3
synovium 1
Il1 (Mus musculus)
Adamts1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 86.84 High High
Inflammation 8 69.24 Quite High
metalloproteinase 22 5.00 Very Low Very Low Very Low
Osteoarthritis 22 5.00 Very Low Very Low Very Low
Arthritis 16 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 69.24 Quite High
Alzheimer's Dementia 2 67.32 Quite High
Necrosis 4 56.28 Quite High
Cancer 4 55.92 Quite High
Adenocarcinoma 2 43.96 Quite Low
Congenital Anomalies 8 36.40 Quite Low
Growth Problems 2 34.04 Quite Low
Syndrome 6 32.52 Quite Low
Arthritis 22 5.00 Very Low Very Low Very Low
Osteoarthritis 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, studies in human articular cartilage and bovine nasal cartilage and synovium suggest that the expression of ADAMTS-4 and -5 mRNA is relatively insensitive to retinoic acid or IL-1?
IL-1 Regulation (insensitive) of Gene_expression (expression) of ADAMTS in nasal cartilage
1) Confidence 0.03 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175049 Disease Relevance 0.37 Pain Relevance 0.17
However, studies in human articular cartilage and bovine nasal cartilage and synovium suggest that the expression of ADAMTS-4 and -5 mRNA is relatively insensitive to retinoic acid or IL-1?
IL-1 Regulation (insensitive) of in synovium Gene_expression (expression) of ADAMTS in nasal cartilage
2) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175049 Disease Relevance 0.37 Pain Relevance 0.17

General Comments

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