INT185019

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Context Info
Confidence 0.21
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDC6) nucleoplasm (CDC6) mitosis (CDC6)
nucleus (CDC6) cell division (CDC6) cytoplasm (CDC6)
CDC6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 31 96.88 Very High Very High Very High
withdrawal 2 93.92 High High
metalloproteinase 2 41.20 Quite Low
cytokine 1 36.76 Quite Low
psoriasis 3 15.60 Low Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 96.88 Very High Very High Very High
Skin Cancer 5 90.48 High High
Cancer 103 65.68 Quite High
Breast Cancer 26 27.20 Quite Low
Lobular Carcinoma 1 19.36 Low Low
Psoriasis 5 17.68 Low Low
Apoptosis 10 5.00 Very Low Very Low Very Low
Colon Cancer 9 5.00 Very Low Very Low Very Low
Metastasis 5 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MAL2, WIPF2 and CDC6 were not associated with any specific molecular subtype [38].
CDC6 Binding (associated) of
1) Confidence 0.21 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.12 Pain Relevance 0
Cdc-6, which are regulated in response to mitogenic signals, binds PCNA and is required for initiation of DNA replication [34], was also repressed at both 12 and 24 hrs after NAC treatment, implying programs involving withdrawal of mitogenic factors as important mechanisms for NAC mediated inhibition of proliferation and increased differentiation in NHEK cells.
Cdc-6 Binding (binds) of associated with withdrawal
2) Confidence 0.09 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.19 Pain Relevance 0.13

General Comments

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