INT185144

Context Info Confidence 0.00 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.29

cytoplasm (Prkca, Snrpd1) nucleus (Prkca, Snrpd1) mitochondrion (Prkca) endoplasmic reticulum (Prkca) enzyme binding (Prkca) protein complex (Prkca)

Anatomy Link Frequency mesenteric vein 1 Prkca (Mus musculus) Snrpd1 (Mus musculus)

Pain Link Frequency Relevance Heat Kinase C 57 100.00 Clonidine 26 67.28 potassium channel 1 63.80 antagonist 4 55.20 Calcium channel 3 36.72 tetrodotoxin 3 5.00 conotoxin 3 5.00 Neurotransmitter 3 5.00 agonist 3 5.00 Action potential 1 5.00

Disease Link Frequency Relevance Heat Increased Venous Pressure Under Development 10 84.60 Overdose 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We used canine isolated mesenteric vein to test the hypothesis that EFS-induced SMD is mediated by PI3K and PKC.

PKC Positive_regulation (mediated) of SMD in mesenteric vein associated with kinase c

1) Confidence 0.00 Published 2005 Journal BMC Physiol Section Body Doc Link PMC1183225 Disease Relevance 0.16 Pain Relevance 0.29

General Comments

This test has worked.