INT185313

Context Info Confidence 0.20 First Reported 2005 Last Reported 2010 Negated 2 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 0.49 Pain Relevance 0.39

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)

Anatomy Link Frequency follicles 2 Tlr4 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 40 89.40 Inflammation 44 67.32 Inflammatory response 4 67.28 chemokine 20 64.72 anesthesia 3 5.00 Inflammatory stimuli 2 5.00 Inflammatory mediators 2 5.00 tolerance 2 5.00 rheumatoid arthritis 2 5.00 ketamine 1 5.00

Disease Link Frequency Relevance Heat Infection 30 71.84 INFLAMMATION 51 67.32 Lung Cancer 2 53.52 Sprains And Strains 48 36.08 Francisella Infection 19 5.00 Immunization 7 5.00 Necrosis 6 5.00 Cancer 6 5.00 Disease 5 5.00 Mycobacterial Infection 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The total area occupied by lymphoid follicles was larger in the LPS+rPorB/challenged group (?

Regulation (larger) of Transcription (group) of LPS in follicles

1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2886834 Disease Relevance 0.25 Pain Relevance 0.07

mRNA expression, there were no significant changes in COX-2 mRNA expression of LPS versus LPS plus parthenolide co-treated animals.

Neg (no) Regulation (changes) of Transcription (expression) of LPS

2) Confidence 0.16 Published 2005 Journal J Inflamm (Lond) Section Body Doc Link PMC1185559 Disease Relevance 0.12 Pain Relevance 0.16

mRNA expression, there were no significant changes in COX-2 mRNA expression of LPS versus LPS plus parthenolide co-treated animals.

Neg (no) Regulation (changes) of Transcription (expression) of LPS

3) Confidence 0.12 Published 2005 Journal J Inflamm (Lond) Section Body Doc Link PMC1185559 Disease Relevance 0.12 Pain Relevance 0.16

General Comments

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