INT185455

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC1, Timp1) proteinaceous extracellular matrix (Timp1) plasma membrane (MUC1)
nucleus (MUC1) cytoplasm (MUC1)
MUC1 (Homo sapiens)
Timp1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 100.00 Very High Very High Very High
Calcitonin gene-related peptide 1 84.16 Quite High
cytokine 1 72.32 Quite High
Inflammation 24 50.00 Quite Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 78 96.52 Very High Very High Very High
Disease 40 88.48 High High
Skin Cancer 8 86.00 High High
Crohn's Disease 109 78.68 Quite High
Adhesions 6 5.04 Very Low Very Low Very Low
INFLAMMATION 24 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Colon Cancer 5 5.00 Very Low Very Low Very Low
Wound Healing 3 5.00 Very Low Very Low Very Low
Colon Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genes that were significantly up-regulated in both microarray and real-time PCR in the two IBD subtypes (compared to normal controls), include cadherin-11 (CDH11), decay accelerating factor for complement (DAF), immunoglobulin heavy constant gamma 1 (IGHG1), mucin 1 (MUC1), phospholipase A2, group IIA (PLA2G2A), and tissue inhibitor of metalloproteinase 1 (TIMP1).
MUC1 Negative_regulation (inhibitor) of TIMP1 associated with inflammatory bowel disease and metalloproteinase
1) Confidence 0.06 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1188246 Disease Relevance 0.84 Pain Relevance 0.13

General Comments

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