INT186370

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Irf8, Irf1) DNA binding (Irf8, Irf1)
Irf8 (Mus musculus)
Irf1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 53 50.00 Quite Low
Inflammation 11 10.72 Low Low
Central nervous system 7 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 214 96.40 Very High Very High Very High
Infection 197 96.24 Very High Very High Very High
Adhesions 1 90.20 High High
Viral Infection 15 63.76 Quite High
Toxicity 3 39.40 Quite Low
INFLAMMATION 13 10.72 Low Low
Targeted Disruption 3 8.80 Low Low
Herpes Simplex Virus 14 5.00 Very Low Very Low Very Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Cancer 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another potential mechanism in the synergistic induction of iNOS could involve complex formation of IFN consensus sequence-binding protein (ICSBP or IRF-8) and IRF-1, which is also important for high-output NO production but has still not been studied in HSV infections [416].
Regulation (involve) of IRF-8 Binding (formation) of IRF-1 associated with cold sores and infection
1) Confidence 0.04 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 0.82 Pain Relevance 0

General Comments

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