INT187111

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Context Info
Confidence 0.23
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (TIMP2, MMP9) peptidase activity (MMP9) extracellular space (MMP9)
proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9) protein complex (MMP9)
Anatomy Link Frequency
blood 2
TIMP2 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 52 100.00 Very High Very High Very High
rheumatoid arthritis 126 97.54 Very High Very High Very High
methotrexate 10 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Etanercept 2 5.00 Very Low Very Low Very Low
Leflunomide 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 126 97.54 Very High Very High Very High
Arthropathy 14 87.20 High High
Arthritis 10 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Autoimmune Disease 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Rupture 4 5.00 Very Low Very Low Very Low
Chondrocalcinosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, immunoglobulin G (IgG) from blood samples of RA patients possessing TIMP antibodies was isolated on protein A–sepharose and tested for the in vitro ability to neutralize TIMP-2-dependent effects on metalloproteinase 9 (MMP9).
TIMP-2 Regulation (effects) of metalloproteinase 9 in blood associated with metalloproteinase and rheumatoid arthritis
1) Confidence 0.23 Published 2005 Journal Arthritis Res Ther Section Abstract Doc Link PMC1257425 Disease Relevance 0.73 Pain Relevance 0.48
In addition, immunoglobulin G (IgG) from blood samples of RA patients possessing TIMP antibodies was isolated on protein A–sepharose and tested for the in vitro ability to neutralize TIMP-2-dependent effects on metalloproteinase 9 (MMP9).
TIMP-2 Regulation (effects) of MMP9 in blood associated with metalloproteinase and rheumatoid arthritis
2) Confidence 0.23 Published 2005 Journal Arthritis Res Ther Section Abstract Doc Link PMC1257425 Disease Relevance 0.73 Pain Relevance 0.48

General Comments

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