INT187223

Context Info Confidence 0.09 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.64 Pain Relevance 0.32

cell differentiation (Tnfsf11) extracellular space (Tnfsf11) extracellular region (Tnfsf11) plasma membrane (Tnfsf11) intracellular (Tnfsf11) cytoplasm (Tnfsf11)

Il1 (Mus musculus) Tnfsf11 (Mus musculus)

Pain Link Frequency Relevance Heat chemokine 3 98.40 Arthritis 54 86.84 rheumatoid arthritis 33 74.96 cytokine 36 50.32 Inflammation 24 49.60 Inflammatory mediators 4 5.00 Freund adjuvant 2 5.00 Peripheral nervous system 1 5.00 Pain 1 5.00 metalloproteinase 1 5.00

Disease Link Frequency Relevance Heat Arthritis 64 88.64 Rheumatoid Arthritis 33 74.96 Hypercalcemia 11 59.04 INFLAMMATION 28 49.60 Immunization 6 5.00 Pressure And Volume Under Development 5 5.00 Osteoporosis 4 5.00 Necrosis 3 5.00 Autoimmune Disease 3 5.00 Cancer 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

RANKL expression can be upregulated by bone resorbing factors such as glucocorticoids, vitamin D, IL-1?

IL-1 Positive_regulation (upregulated) of Gene_expression (expression) of RANKL

1) Confidence 0.09 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257432 Disease Relevance 0.64 Pain Relevance 0.32

General Comments

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