INT187506

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 2.27
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Cebpg) nucleus (Cebpg) DNA binding (Cebpg)
transcription factor binding (Cebpg)
Cebpg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 5 89.28 High High
Inflammation 116 84.76 Quite High
cytokine 136 82.80 Quite High
ischemia 38 80.68 Quite High
agonist 23 74.24 Quite High
Inflammatory response 21 51.88 Quite High
Inflammatory mediators 33 50.00 Quite Low
cINOD 7 48.24 Quite Low
anesthesia 1 45.28 Quite Low
COX-2 inhibitor 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 38 96.16 Very High Very High Very High
Stress 78 94.40 High High
Repression 17 91.44 High High
Fibrosis 6 89.28 High High
INFLAMMATION 174 84.76 Quite High
Cv Unclassified Under Development 32 80.68 Quite High
Lung Injury 7 79.88 Quite High
Cv General 4 Under Development 4 73.04 Quite High
Alzheimer's Dementia 45 10.80 Low Low
Disease 110 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The polymorphism may alter the binding affinity of C/EBP at this locus.
C/EBP Binding (affinity) of
1) Confidence 0.47 Published 2010 Journal BMC Genet Section Body Doc Link PMC2920856 Disease Relevance 0 Pain Relevance 0
CHOP, also known as GADD153, is a member of the C/EBP transcription factor family; it forms heterodimers with other C/EBPs (Ron and Habener 1992).
C/EBP Binding (forms) of
2) Confidence 0.36 Published 2010 Journal Acta Orthopaedica Section Body Doc Link PMC2895349 Disease Relevance 1.82 Pain Relevance 0.21
The polymorphism may alter the binding affinity of C/EBP at this locus.
C/EBP Binding (binding) of
3) Confidence 0.36 Published 2010 Journal BMC Genet Section Body Doc Link PMC2920856 Disease Relevance 0 Pain Relevance 0
B and C/EBP, which have been suggested to interact with PPARs in different experimental systems (34,35).
C/EBP Binding (interact) of
4) Confidence 0.35 Published 2011 Journal Nucleic Acids Research Section Body Doc Link PMC3017614 Disease Relevance 0.35 Pain Relevance 0.24
B, AP-1, C/EBP and CREB binding activity
C/EBP Binding (activity) of
5) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1262754 Disease Relevance 0.05 Pain Relevance 0.14
Briefly, the protein-binding DNA sequences (previously labeled with 32P) of C/EBP, NF?
C/EBP Binding (binding) of
6) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1262754 Disease Relevance 0 Pain Relevance 0
B, AP-1, C/EBP and CREB binding activity
C/EBP Binding (binding) of
7) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1262754 Disease Relevance 0.05 Pain Relevance 0.14

General Comments

This test has worked.

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