INT188433

From wiki-pain
Revision as of 21:18, 22 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 2.03
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
Anatomy Link Frequency
satellite cells 2
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 111 98.84 Very High Very High Very High
rheumatoid arthritis 30 95.36 Very High Very High Very High
methotrexate 16 85.92 High High
cytokine 40 67.04 Quite High
Arthritis 16 50.00 Quite Low
Pain 4 39.16 Quite Low
anakinra 2 35.60 Quite Low
Inflammatory marker 7 34.36 Quite Low
Etanercept 2 11.52 Low Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 133 98.84 Very High Very High Very High
Dyspnea 12 98.56 Very High Very High Very High
Keloid Scars 103 96.40 Very High Very High Very High
Cancer 35 95.72 Very High Very High Very High
Necrosis 7 95.48 Very High Very High Very High
Rheumatoid Arthritis 30 95.36 Very High Very High Very High
Disease 71 89.92 High High
Mycobacterial Infection 2 83.24 Quite High
Infection 56 82.40 Quite High
Fever 12 73.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The positive association between IL-6 and each pollutant declined with moving averages longer than 6 days.
Negative_regulation (declined) of IL-6 Binding (association) of
1) Confidence 0.42 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2831955 Disease Relevance 0 Pain Relevance 0
IL-6 positive satellite cells enumeration
Negative_regulation (positive) of IL-6 Binding (enumeration) of in satellite cells
2) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2696599 Disease Relevance 0 Pain Relevance 0
It has been shown to compete for both the membrane-bound and soluble forms of human IL-6 receptor, thus inhibiting the binding of IL-6 to its receptor and its pro-inflammatory activity [20].
Negative_regulation (inhibiting) of IL-6 Binding (binding) of associated with inflammation
3) Confidence 0.28 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297576 Disease Relevance 0.47 Pain Relevance 0.05
We then explored the interaction between IL-6 and IL-17 and determine whether the IL-17/IL-6 axis contributes to the regulation of the keloid niche.
Negative_regulation (explored) of IL-6 Spec (determine) Binding (interaction) of associated with keloid scars
4) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2771422 Disease Relevance 0.10 Pain Relevance 0
In another study of multiple serum biomarkers in 20 hospitalized patients with exacerbation, reduction in interleukin-6 (IL-6) and interleukin-8 (IL-8) correlated with decrease in dyspnea during recovery from exacerbation, while decreases in IL-6 and tumor necrosis factor (TNF?)
Negative_regulation (reduction) of IL-6 Binding (interleukin-8) of associated with necrosis, cancer and dyspnea
5) Confidence 0.05 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2528209 Disease Relevance 0.36 Pain Relevance 0
In another study of multiple serum biomarkers in 20 hospitalized patients with exacerbation, reduction in interleukin-6 (IL-6) and interleukin-8 (IL-8) correlated with decrease in dyspnea during recovery from exacerbation, while decreases in IL-6 and tumor necrosis factor (TNF?)
Negative_regulation (reduction) of interleukin-6 Binding (interleukin-8) of associated with necrosis, cancer and dyspnea
6) Confidence 0.05 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2528209 Disease Relevance 0.36 Pain Relevance 0
Tocilizumab (TCZ) is a humanized monoclonal antibody against IL-6 receptors and inhibits binding between IL-6 and IL-6 receptors [4, 5].
Negative_regulation (inhibits) of IL-6 Binding (binding) of
7) Confidence 0.03 Published 2009 Journal Rheumatol Int Section Body Doc Link PMC2877340 Disease Relevance 0.74 Pain Relevance 0.52

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox