INT189392

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Context Info
Confidence 0.57
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 10
Disease Relevance 7.69
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MFI2) plasma membrane (MFI2)
Anatomy Link Frequency
internal 1
MFI2 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 56 99.50 Very High Very High Very High
Osteoarthritis 128 99.40 Very High Very High Very High
depression 251 96.32 Very High Very High Very High
Leflunomide 60 94.64 High High
Pain 56 72.36 Quite High
Inflammation 53 71.64 Quite High
corticosteroid 12 69.24 Quite High
cytokine 32 68.60 Quite High
rheumatoid arthritis 308 68.00 Quite High
tolerance 4 54.92 Quite High
Disease Link Frequency Relevance Heat
Fatigue 558 100.00 Very High Very High Very High
Frailty 136 99.40 Very High Very High Very High
Rheumatoid Arthritis 488 99.12 Very High Very High Very High
Anxiety Disorder 251 98.64 Very High Very High Very High
Disease 130 96.36 Very High Very High Very High
Depression 266 96.32 Very High Very High Very High
Disease Progression 24 84.20 Quite High
Chronic Fatigue Syndrome 246 82.12 Quite High
Autoimmune Disease 28 79.80 Quite High
Pain 54 72.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The MFI-20 comprises five subscales: general fatigue, physical fatigue, mental fatigue, reduced activity, and reduced motivation [2].
Gene_expression (comprises) of MFI-20 associated with fatigue
1) Confidence 0.57 Published 2009 Journal Popul Health Metr Section Body Doc Link PMC2801470 Disease Relevance 1.50 Pain Relevance 0.10
Relationships among five MFI-20 subscales
Gene_expression (subscales) of MFI-20
2) Confidence 0.57 Published 2009 Journal Popul Health Metr Section Body Doc Link PMC2801470 Disease Relevance 0.58 Pain Relevance 0
Associations of age and sex with MFI-20 subscale scores
Gene_expression (scores) of MFI-20
3) Confidence 0.57 Published 2009 Journal Popul Health Metr Section Body Doc Link PMC2801470 Disease Relevance 0.45 Pain Relevance 0
The MFI-20 item subscales exhibited adequate internal consistency reliability with Cronbach's ?
Gene_expression (item) of MFI-20 in internal
4) Confidence 0.57 Published 2009 Journal Popul Health Metr Section Body Doc Link PMC2801470 Disease Relevance 0.69 Pain Relevance 0.23
for the five MFI-20 scales were: general fatigue: 0.83; physical fatigue: 0.81; reduced activity: 0.82; reduced motivation: 0.71; and mental fatigue: 0.86.
Gene_expression (scales) of MFI-20 associated with fatigue
5) Confidence 0.57 Published 2009 Journal Popul Health Metr Section Body Doc Link PMC2801470 Disease Relevance 0.75 Pain Relevance 0
medians of the MFI general fatigue (?
Gene_expression (general) of MFI associated with fatigue
6) Confidence 0.20 Published 2005 Journal BMC Med Section Body Doc Link PMC1334212 Disease Relevance 1.39 Pain Relevance 0
The MFI levels for p-AKT, p-CBL and p-JNK were statistically higher (p<0.05) in ERA patient PBMCs compared with OA patient PBMCs, in the CD4+, CD8+ and CD20+ compartments (Figure 3).
Gene_expression (levels) of MFI associated with rheumatoid arthritis and osteoarthritis
7) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 0.87 Pain Relevance 0.19
The MFI values of a subset of these effectors, p-AKT, p-CBL and p-JNK, were consistently higher in all three cell populations in ERA patient PBMCs compared to OA patient PBMCs.
Gene_expression (values) of MFI associated with rheumatoid arthritis and osteoarthritis
8) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 1.45 Pain Relevance 0.35
MTX therapy reduced p-STAT1 MFI values in CD20+ cells (p?
Gene_expression (values) of MFI associated with methotrexate
9) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 0 Pain Relevance 0.24
Reductions in MFI values for p-AKT, p-p38, p-JNK, p-PLC?
Gene_expression (values) of MFI
10) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 0 Pain Relevance 0.34

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