INT189607

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HIF1A) signal transduction (HIF1A) nucleolus (HIF1A)
nucleus (HIF1A) transcription factor binding (HIF1A) cytoplasm (HIF1A)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 8 22.92 Low Low
ischemia 18 5.00 Very Low Very Low Very Low
cytokine 14 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
Serotonin 5 5.00 Very Low Very Low Very Low
Thoracotomy 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 15 100.00 Very High Very High Very High
Pulmonary Hypertension 85 97.64 Very High Very High Very High
Hypertension 2 92.24 High High
Cancer 5 87.92 High High
Increased Venous Pressure Under Development 5 74.76 Quite High
Herpes Simplex Virus 2 70.88 Quite High
Peripheral Arterial Disease 16 64.92 Quite High
Coronary Artery Disease 18 57.40 Quite High
Disease 22 57.04 Quite High
Metastasis 1 51.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, there is a feedback loop whereby the HIF-1 complex, formed under conditions of hypoxia, upregulates PHD2 [43].
Regulation (upregulates) of HIF-1 Binding (complex) of associated with hypoxia
1) Confidence 0.06 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 0.86 Pain Relevance 0
Intracellular oxygen concentration regulates HIF-1 activity by influencing both stability and transcriptional activity of the HIF-1?
Regulation (influencing) of HIF-1 Binding (activity) of
2) Confidence 0.05 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676804 Disease Relevance 0.32 Pain Relevance 0
Intracellular oxygen concentration regulates HIF-1 activity by influencing both stability and transcriptional activity of the HIF-1?
Regulation (regulates) of HIF-1 Binding (activity) of
3) Confidence 0.05 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676804 Disease Relevance 0.31 Pain Relevance 0

General Comments

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