INT190860

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Context Info
Confidence 0.21
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.61
Pain Relevance 3.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkca) endoplasmic reticulum (Prkca) enzyme binding (Prkca)
protein complex (Prkca) cytoplasm (Prkca) cytosol (Prkca)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 161 100.00 Very High Very High Very High
opioid receptor 168 99.28 Very High Very High Very High
Morphine 154 95.24 Very High Very High Very High
Glutamate 22 92.56 High High
Hyperalgesia 3 78.40 Quite High
Pain 8 77.72 Quite High
Neurotransmitter 6 74.48 Quite High
long-term potentiation 8 69.92 Quite High
agonist 18 65.60 Quite High
Analgesic 40 59.36 Quite High
Disease Link Frequency Relevance Heat
Virus Diseases 94 99.84 Very High Very High Very High
Infection 20 99.68 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 95.36 Very High Very High Very High
Death 3 93.12 High High
Apoptosis 2 87.52 High High
Nociception 35 87.04 High High
Hyperalgesia 3 78.40 Quite High
Pain 12 77.72 Quite High
Coagulation Disorder 2 75.80 Quite High
Borna Disease 5 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, we showed here that the activation and membrane translocation of PKC isoforms were not affected by BDV infection.
Neg (not) Regulation (affected) of Localization (translocation) of PKC associated with virus diseases, kinase c and infection
1) Confidence 0.21 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1401496 Disease Relevance 0.80 Pain Relevance 0.65
association involves the cysteine rich domains in the regulatory C1 region of PKC?
Regulation (involves) of Localization (region) of PKC associated with kinase c
2) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0.18 Pain Relevance 1.16
association involves the cysteine rich domains in the regulatory C1 region of PKC?
Regulation (regulatory) of Localization (region) of PKC associated with kinase c
3) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0.18 Pain Relevance 1.12
/PKC pathway: intracellular calcium release, sensitisation of TRPV1, and translocation of the epsilon isoform of PKC (PKC?)
Regulation (intracellular) of Localization (release) of PKC
4) Confidence 0.08 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2956715 Disease Relevance 0.45 Pain Relevance 0.18

General Comments

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