INT192090

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Context Info
Confidence 0.46
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.15
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Rara) nucleus (Rara) enzyme binding (Rara)
DNA binding (Rara) transcription factor binding (Rara) cytoplasm (Rara)
Anatomy Link Frequency
immune cells 1
CAR 1
Rara (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 96 98.56 Very High Very High Very High
Central nervous system 51 89.52 High High
agonist 35 88.52 High High
dexamethasone 124 86.64 High High
Inflammation 157 67.52 Quite High
Peripheral nerve injury 6 67.44 Quite High
Peripheral nervous system 18 58.72 Quite High
cytokine 45 36.16 Quite Low
corticosteroid 11 10.32 Low Low
Bile 39 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 28 98.80 Very High Very High Very High
Injury 61 97.60 Very High Very High Very High
Rheumatoid Arthritis 305 95.44 Very High Very High Very High
Hypersensitivity 25 94.28 High High
Frailty 60 89.96 High High
Autoimmune Disease 1 89.64 High High
Infection 5 68.04 Quite High
INFLAMMATION 200 67.52 Quite High
Inflammatory Bowel Disease 32 67.04 Quite High
Nervous System Injury 12 66.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
displayed a nuclear localization of RAR?
Localization (localization) of RAR
1) Confidence 0.46 Published 2007 Journal PPAR Research Section Body Doc Link PMC1950239 Disease Relevance 1.19 Pain Relevance 0.13
displayed a nuclear localization of RAR?
Localization (localization) of RAR
2) Confidence 0.46 Published 2007 Journal PPAR Research Section Body Doc Link PMC1950239 Disease Relevance 1.19 Pain Relevance 0.13
specifically RAR?
Localization (specifically) of RAR
3) Confidence 0.42 Published 2007 Journal PPAR Research Section Body Doc Link PMC1950239 Disease Relevance 0.35 Pain Relevance 0.37
Similarly, action of vitamin A, so called retinol, is mediated over antigen presenting cells (APC) through specific intracellular receptors (RAR, RXR) [10,11], which are present in the immune cells.
Localization (present) of RAR in immune cells
4) Confidence 0.33 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2773769 Disease Relevance 0.26 Pain Relevance 0
B and other nuclear receptors, since RXR is a common partner for many nuclear receptors including CAR, VDR, RAR, TR, LXR and PPARs [Xie and Tian, 2006].
Localization (receptors) of RAR in CAR
5) Confidence 0.14 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0.50 Pain Relevance 0.13
Finally, targeted deletion of RAR-?
Localization (deletion) of RAR
6) Confidence 0.06 Published 2006 Journal Respir Res Section Body Doc Link PMC1448204 Disease Relevance 0.67 Pain Relevance 0.13

General Comments

This test has worked.

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