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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 7
Disease Relevance 1.24
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx1) plasma membrane (P2rx1) protein complex (P2rx1)
Anatomy Link Frequency
C8-B4 2
neurons 1
ganglion 1
P2rx1 (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 150 98.74 Very High Very High Very High
Glutamate 26 93.96 High High
gABA 14 93.16 High High
cerebral cortex 3 86.16 High High
imagery 48 82.76 Quite High
Hippocampus 11 81.96 Quite High
adenocard 21 80.16 Quite High
Neurotransmitter 23 50.00 Quite Low
Pain 36 22.36 Low Low
dorsal root ganglion 19 6.80 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 212 98.74 Very High Very High Very High
Apoptosis 4 93.48 High High
Nociception 18 32.64 Quite Low
Injury 2 24.00 Low Low
Pain 46 22.36 Low Low
Stress 1 17.28 Low Low
Neuropathic Pain 46 5.00 Very Low Very Low Very Low
Headache 14 5.00 Very Low Very Low Very Low
Targeted Disruption 11 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the seven P2X subunits, we failed to detect transcripts for P2X1, P2X2, and P2X5 above levels observed in samples that were analyzed identically, but contained no template for PCR, suggesting that these transcripts are found at negligible background levels.
Transcription (transcripts) of P2X1
1) Confidence 0.27 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.10
We used qPCR to shed light on the P2X receptor transcripts expressed in resting and activated C8-B4 cells.
Transcription (expressed) of P2X in C8-B4
2) Confidence 0.27 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.16
We next assessed if rat and mouse TG neurons in culture demonstrated changes in the levels of mRNA transcripts of P2X and TRPV1 receptors with respect to the ganglion.
Transcription (transcripts) of P2X in neurons associated with ganglion cysts and trigeminal ganglion
3) Confidence 0.25 Published 2006 Journal Mol Pain Section Body Doc Link PMC1448213 Disease Relevance 0.64 Pain Relevance 0.11
Of the seven P2X subunits, we failed to detect transcripts for P2X1, P2X2, and P2X5 above levels observed in samples that were analyzed identically, but contained no template for PCR, suggesting that these transcripts are found at negligible background levels.
Transcription (transcripts) of P2X
4) Confidence 0.23 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.10
To quantify changes in neuron specific mRNA neosynthesis for P2X and TRPV1 receptors in culture with respect to the ganglion, we performed real time RT-PCR experiments as a sensitive method to detect changes in gene expression [15].
Transcription (neosynthesis) of P2X in ganglion associated with ganglion cysts
5) Confidence 0.18 Published 2006 Journal Mol Pain Section Body Doc Link PMC1448213 Disease Relevance 0.59 Pain Relevance 0.08
qPCR analysis of P2X subunit transcript levels in resting and activated C8-B4 cells
Transcription (levels) of P2X in C8-B4
6) Confidence 0.18 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.17
Structure, pharmacology, and signal transduction of P2X receptors
Transcription (transduction) of P2X
7) Confidence 0.15 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072919 Disease Relevance 0 Pain Relevance 0.20

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