INT193376

Context Info Confidence 0.75 First Reported 2006 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 7 Total Number 8 Disease Relevance 1.60 Pain Relevance 0.20

mitochondrion (WASF1) cytoskeleton (WASF1) protein complex assembly (WASF1) cytoplasm (WASF1)

Anatomy Link Frequency platelets 1 WASF1 (Homo sapiens)

Pain Link Frequency Relevance Heat medulla 20 96.72 repetitive firing 5 72.20 Action potential 25 68.92 ischemia 40 50.00 Inflammation 6 42.52 cerebral cortex 5 40.96 Pain 6 23.72 spastic colon 23 5.00 Crohn's disease 22 5.00 imagery 21 5.00

Disease Link Frequency Relevance Heat Cicatrix 7 100.00 Myocardial Infarction 47 98.08 Left Ventricular Dysfunction 1 93.60 Dilated Cardiomyopathy 5 86.40 Heart Disease 5 76.68 Hypertension 6 76.12 Coronary Heart Disease 3 74.08 Cv Unclassified Under Development 21 72.76 Stress 8 64.72 Coronary Artery Disease 60 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The expression of cortactin, Scar/WAVE2 and WASp was the same in both WT and HS1-/- platelets indicating that there was no compensatory up-regulation of these proteins (Figure 2E).

Gene_expression (expression) of Scar in platelets associated with cicatrix

1) Confidence 0.75 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.51 Pain Relevance 0

audA-wave = "auditory-system A-wave"

Gene_expression (system) of A-wave

2) Confidence 0.38 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0 Pain Relevance 0.05

If we assume that a given cortical cell fires at the same phase of each cycle in a sustained A-wave oscillation, there might be some stimulation rate at which the cell is about to fire due to the most recent stimulus, but has just fired as a later "cycle" to an earlier stimulus.

Gene_expression (oscillation) of A-wave

3) Confidence 0.38 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0 Pain Relevance 0.04

When a changing sensory input results in a markedly-uneven firing rate, then the "figure" thus identified is rapidly analyzed with the brief A-wave responses (below STZ).

Spec (analyzed) Gene_expression (responses) of A-wave

4) Confidence 0.38 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0 Pain Relevance 0.06

audA-wave = "auditory-system A-wave"

Gene_expression (system) of audA-wave

5) Confidence 0.38 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0 Pain Relevance 0.05

Some of our visA-wave recordings show them and some do not (see Figs. 4 and 6); we do not understand why.

Gene_expression (recordings) of visA-wave

6) Confidence 0.38 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0 Pain Relevance 0

When integrated in fully automated instruments such as the Transgenomic WAVE systems (http://www.transgenomic.com/), DHPLC analysis offers several advantages over

Gene_expression (systems) of WAVE

7) Confidence 0.09 Published 2008 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2648627 Disease Relevance 0 Pain Relevance 0

Microvolt T-wave alternans

Gene_expression (alternans) of T-wave

8) Confidence 0.04 Published 2010 Journal GMS German Medical Science Section Body Doc Link PMC2975259 Disease Relevance 1.09 Pain Relevance 0

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