INT194938

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Context Info
Confidence 0.29
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.48
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PTPN6) cell proliferation (PTPN6) cytosol (PTPN6)
nucleus (PTPN6) cytoplasm (PTPN6)
PTPN6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 7 97.04 Very High Very High Very High
Arthritis 1 15.36 Low Low
corticosteroid 6 5.00 Very Low Very Low Very Low
Antihistamine 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 97.04 Very High Very High Very High
Adhesions 3 75.32 Quite High
Systemic Lupus Erythematosus 43 67.16 Quite High
Autoimmune Disease 9 62.96 Quite High
Disease 34 41.24 Quite Low
Increased Venous Pressure Under Development 3 38.08 Quite Low
Nephritis 3 37.48 Quite Low
Renal Disease 1 32.80 Quite Low
Apoptosis 1 20.72 Low Low
Renal Failure 1 19.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It also demonstrated an abundance of haematopoietic specific elements such as RUNX, WAS, PTPN6, HCLS1 in eEPCs (Figure 2B).
Regulation (abundance) of PTPN6
1) Confidence 0.29 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC2881111 Disease Relevance 0.16 Pain Relevance 0.08
SHP-1 is a tyrosine phosphatase that negatively regulates several intracellular signaling pathways, including the calcium pathway, through dephosphorylation of signaling intermediates, such as Lyn and Syk.
Regulation (regulates) of SHP-1
2) Confidence 0.05 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526638 Disease Relevance 0.32 Pain Relevance 0

General Comments

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