INT195076

Context Info Confidence 0.62 First Reported 2006 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.63 Pain Relevance 0.17

cell differentiation (Cspg4) cell proliferation (Cspg4) signal transduction (Cspg4) plasma membrane (Cspg4) intracellular (Cspg4) signal transducer activity (Cspg4)

Anatomy Link Frequency neocortex 1 Cspg4 (Mus musculus)

Pain Link Frequency Relevance Heat Glutamate 23 76.72 cytokine 11 5.00 Inflammation 6 5.00 Nerve growth factor 4 5.00 Inflammatory mediators 3 5.00 Central nervous system 2 5.00 ketamine 2 5.00 Multiple sclerosis 2 5.00 Spinal cord 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Injury 55 90.52 Brain Injury 10 81.36 Stab Wounds 15 78.48 Cicatrix 6 59.20 Disease 12 54.88 INFLAMMATION 10 5.00 Epilepsy 6 5.00 Penetrating Head Injuries 5 5.00 Death 3 5.00 Anaplastic Astrocytoma 3 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The number of Cspg4 transcripts/cell was then calculated assuming ?

Transcription (transcripts) of Cspg4

1) Confidence 0.62 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973945 Disease Relevance 0.05 Pain Relevance 0

into the neocortex of WT and IL-1R1-null mice and analyzed CSPG-4 levels after 5 days.

Spec (analyzed) Transcription (levels) of CSPG-4 in neocortex

2) Confidence 0.38 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1533808 Disease Relevance 0.58 Pain Relevance 0.17

General Comments

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