INT195087

Context Info Confidence 0.12 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.83 Pain Relevance 0.09

mitochondrion (Pars2) translation (Pars2) ligase activity (Pars2) cytoplasm (Pars2)

Anatomy Link Frequency plasma 1 Pars2 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 6 97.84 cytokine 9 89.44 Glutamate 23 5.00 Nerve growth factor 4 5.00 Inflammatory mediators 3 5.00 ketamine 2 5.00 Central nervous system 1 5.00 anesthesia 1 5.00 Multiple sclerosis 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Injury 55 99.48 INFLAMMATION 10 97.84 Stab Wounds 15 96.04 Penetrating Head Injuries 5 84.00 Hypertrophy 3 18.04 Brain Injury 10 5.00 Cicatrix 6 5.00 Disease 4 5.00 Death 3 5.00 Gliosis 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

During injury thrombin is released and cleaves the protease-activated receptors (PARs), which subsequently induce plasma extravasation and inflammation.

Protein_catabolism (cleaves) of PARs in plasma associated with inflammation and injury

1) Confidence 0.12 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1533808 Disease Relevance 0.83 Pain Relevance 0.09

General Comments

This test has worked.