INT196527

Context Info Confidence 0.44 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.74 Pain Relevance 0.51

peptidase activity (MMP1, MMP2) extracellular region (MMP1, MMP2) proteinaceous extracellular matrix (MMP1, MMP2) extracellular space (MMP2) plasma membrane (MMP2) nucleus (MMP2)

MMP1 (Homo sapiens) MMP2 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 53 99.72 Dysuria 1 23.40 Inflammation 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Bladder Cancer 29 90.72 Transitional Cell Carcinoma 26 86.08 Cancer 36 82.52 Disease 5 76.96 Metastasis 11 61.76 Malignant Neoplastic Disease 3 60.40 Recurrence 2 46.84 Hematuria 1 22.92 Genitourinary Tract Cancer 2 10.56 Reprotox - General 1 2 9.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Activated MMP1, MMP3, and latent forms of MMP2 and MMP9 bind to and are inhibited by TIMP1 and TIMP2.

Positive_regulation (Activated) of MMP1 Binding (bind) of MMP2

1) Confidence 0.44 Published 2006 Journal BMC Urol Section Body Doc Link PMC1560390 Disease Relevance 0.74 Pain Relevance 0.51

General Comments

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