INT196635

Context Info Confidence 0.07 First Reported 2006 Last Reported 2006 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.44 Pain Relevance 0.21

cytoplasm (CFTR, CCL5) transport (CFTR) aging (CCL5) enzyme binding (CFTR) protein complex (CFTR) cell-cell signaling (CCL5)

CFTR (Homo sapiens) CCL5 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 34 90.64 fibrosis 6 61.16 cytokine 21 60.32 chemokine 2 47.92 Inflammatory mediators 20 42.36 bradykinin 10 17.20 sodium channel 9 5.00 adenocard 5 5.00 agonist 5 5.00 substance P 3 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 56 90.64 Congenital Anomalies 4 80.96 Disease 9 65.76 Cystic Fibrosis 6 61.16 Pressure And Volume Under Development 4 31.68 Heart Rate Under Development 11 5.00 Diarrhoea 8 5.00 Necrosis 5 5.00 Cancer 5 5.00 Pyelonephritis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CFTR was moreover found to increase RANTES expression independently of its function as a chloride channel in bronchial cell lines [121,122].

CFTR Neg (independently) Positive_regulation (increase) of Gene_expression (expression) of RANTES

1) Confidence 0.07 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0.44 Pain Relevance 0.21

General Comments

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