INT196814

Context Info Confidence 0.17 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.29

cytoplasm (Prkaca, Ppp2ca) nucleus (Prkaca, Ppp2ca) plasma membrane (Prkaca, Ppp2ca) mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca)

Prkaca (Mus musculus) Ppp2ca (Mus musculus)

Pain Link Frequency Relevance Heat Dopamine 119 91.48 agonist 1 66.36 Calcium channel 2 45.60 Glutamate 31 5.00 long-term potentiation 8 5.00 projection neuron 4 5.00 Action potential 4 5.00 Neurotransmitter 3 5.00 imagery 3 5.00 nMDA receptor 2 5.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Additional model simulations show that enhanced activation of PP2A via phosphorylation by PKA is required to produce the decrease in phosphoThr75.

Negative_regulation (decrease) of PKA Positive_regulation (activation) of PP2A

1) Confidence 0.17 Published 2006 Journal PLoS Computational Biology Section Body Doc Link PMC1562452 Disease Relevance 0 Pain Relevance 0.29

General Comments

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