INT19689

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Context Info
Confidence 0.24
First Reported 1983
Last Reported 2006
Negated 1
Speculated 1
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 1.01
Pain Relevance 2.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Tes) plasma membrane (Tes) nucleus (Tes)
protein complex (Tes) cytoplasm (Tes)
Anatomy Link Frequency
sensory nerves 1
respiratory 1
Tes (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Antinociceptive 16 100.00 Very High Very High Very High
Nicotine 3 99.88 Very High Very High Very High
Endogenous opioid 1 99.80 Very High Very High Very High
gABA 3 99.32 Very High Very High Very High
Perioperative pain 5 97.36 Very High Very High Very High
qutenza 9 95.84 Very High Very High Very High
tetrodotoxin 4 95.12 Very High Very High Very High
analgesia 2 93.72 High High
Opioid 1 85.44 High High
tail-flick 2 82.80 Quite High
Disease Link Frequency Relevance Heat
Post Operative Pain 5 97.36 Very High Very High Very High
Nociception 4 86.48 High High
Body Weight 2 82.92 Quite High
Pain 3 67.76 Quite High
Hypothermia 1 61.28 Quite High
Anxiety Disorder 1 53.36 Quite High
Increased Venous Pressure Under Development 1 52.08 Quite High
Neurosis 3 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a recently introduced clinically relevant rat model of TES we have validated and characterized the TES antinociceptive effect, suggesting involvement of the sensory nerves of the rat's scalp in mediating that effect.
Regulation (effect) of TES in sensory nerves associated with antinociceptive
1) Confidence 0.24 Published 2006 Journal Anesth. Analg. Section Abstract Doc Link 16717325 Disease Relevance 0.06 Pain Relevance 0.47
In this study we validated the TES antinociceptive effect in a novel animal model of cutaneously administered TES, when the stimulating conditions mimic the ones used in clinical practice.
Regulation (effect) of TES associated with antinociceptive
2) Confidence 0.24 Published 2004 Journal Anesth. Analg. Section Abstract Doc Link 14980928 Disease Relevance 0.09 Pain Relevance 0.45
It is supposed that endogenous opioid peptides regulate an afferent discharge on the level of sensory endings during TES.
Regulation (regulate) of TES associated with endogenous opioid
3) Confidence 0.24 Published 1990 Journal Biull Eksp Biol Med Section Abstract Doc Link 2083320 Disease Relevance 0 Pain Relevance 0.10
Before and after capsaicin treatment respiratory evaporative heat loss (REHL, w X kg-1), breathing frequency (BF, min-1) and metabolic heat production (M, w X kg-1) were determined in a warm environment (35-38 degrees C) as a function of core temperature, measured in the esophagus (Tes), which was altered by graded heat extraction with a colonic thermode.
Regulation (altered) of Tes in respiratory associated with qutenza
4) Confidence 0.20 Published 1986 Journal Pflugers Arch. Section Abstract Doc Link 3714439 Disease Relevance 0.36 Pain Relevance 0.53
The influence of transcutaneous electrical stimulation (TES) and psychological factors in determining the intensity of acute postoperative pain was examined in a prospective, double-blind controlled trial completed by 30 patients having elective surgery.
Spec (examined) Regulation (influence) of TES associated with perioperative pain
5) Confidence 0.18 Published 1983 Journal Pain Section Abstract Doc Link 6606153 Disease Relevance 0.50 Pain Relevance 0.56
In contrast, these compounds failed to affect TES-, nicotine- and GABA-induced relaxations.
Neg (failed) Regulation (affect) of TES associated with gaba and nicotine
6) Confidence 0.17 Published 1999 Journal J Auton Pharmacol Section Abstract Doc Link 10589974 Disease Relevance 0 Pain Relevance 0.65

General Comments

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