INT197093

Context Info Confidence 0.01 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.64 Pain Relevance 0.19

extracellular space (TNF, IL1B) signal transduction (TNF, IL1B) extracellular region (TNF, IL1B) aging (IL1B) intracellular (TNF) extracellular matrix organization (TNF)

Anatomy Link Frequency lymphatic vessels 2 TNF (Homo sapiens) IL1B (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 13 99.82 Paracetamol 2 5.00 Pain 2 5.00 headache 2 5.00 drug abuse 1 5.00 Inflammation 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Helminth Infection 60 84.92 Death 4 71.04 Hydrocele 12 63.60 Lymphedema 77 57.12 Disease 18 51.12 Cancer 7 36.80 Filariasis 6 16.64 Cervical Cancer 1 15.04 Lymphatic Filariasis 23 5.00 Infection 14 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

This raises the possibility that proinflammatory cytokines such as TNF and IL-1B induced by Wolbachia could affect lymphatic vessels via VEGF-C and its receptor sVEGFR-3.

TNF Regulation (affect) of Positive_regulation (induced) of IL-1B in lymphatic vessels associated with cytokine

1) Confidence 0.01 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1564427 Disease Relevance 0.64 Pain Relevance 0.19

General Comments

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