INT197156

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CAPN7) nucleus (CAPN7) intracellular (CAPN7)
Anatomy Link Frequency
spores 1
CAPN7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neutropenia 4 90.60 High High
Malignant Neoplastic Disease 4 90.08 High High
Aspergillus Infection 36 88.00 High High
Hypersensitivity 6 87.76 High High
Asthma 13 81.92 Quite High
Lymphatic System Cancer 4 81.72 Quite High
Leukemia 4 81.32 Quite High
Pneumonia 36 75.36 Quite High
Opportunistic Infections 4 73.36 Quite High
Invasive Pulmonary Aspergillosis 200 67.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Aspergillus qPCR could reliably detect down to a threshold cycle (Ct) of 41 which is approximately equivalent to 1 fg of Aspergillus genomic DNA or a single copy of the target 18S rRNA gene.
Aspergillus Binding (detect) of
1) Confidence 0.27 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.51 Pain Relevance 0
In addition, the human genomic DNA amounts in the BAL pellets of FN samples were well within the tested limits of cross-reactivity with amplification by Aspergillus qPCR and hence inhibition due to human genomic DNA overload does not appear to be a factor affecting FN results.
Aspergillus Binding (amplification) of
2) Confidence 0.27 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.25 Pain Relevance 0
To determine the specificity of the Aspergillus qPCR, 1 ?
Aspergillus Binding (specificity) of
3) Confidence 0.27 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.46 Pain Relevance 0
Another factor contributing to FPs can be cross-reactivity of the Aspergillus qPCR assay with non-Aspergillus fungi.
Aspergillus Binding (cross) of
4) Confidence 0.27 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.18 Pain Relevance 0
Of the thousands of types of fungal spores found in indoor and outdoor environments, adverse health effects in humans have most frequently been associated with Alternaria, Aspergillus, Cladosporium, Penicillium, and Stachybotrys (Hossain et al. 2004; Jarvis and Miller 2005; O’Driscoll et al. 2005; Stark et al. 2003).
Aspergillus Binding (associated) of in spores
5) Confidence 0.02 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1570051 Disease Relevance 0.51 Pain Relevance 0

General Comments

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