INT197287

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.00
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

immune system process (Ahr) cell morphogenesis (Ahr) DNA binding (Ahr)
response to stress (Ahr) cytoplasm (Ahr) signal transducer activity (Ahr)
Anatomy Link Frequency
brain 4
Ahr (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 8 100.00 Very High Very High Very High
Inflammation 10 76.72 Quite High
anesthesia 4 28.80 Quite Low
Neurotransmitter 15 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
transdermal 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 16 97.08 Very High Very High Very High
Prostate Cancer 56 94.12 High High
Obesity 3 83.52 Quite High
Stress 4 79.36 Quite High
Frailty 6 77.44 Quite High
INFLAMMATION 10 76.72 Quite High
Drug Induced Neurotoxicity 21 64.16 Quite High
Targeted Disruption 21 50.00 Quite Low
Disease Progression 1 41.60 Quite Low
Recurrence 5 37.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Responses of DRESSA mice to AhR agonists
Regulation (Responses) of Gene_expression (agonists) of AhR associated with agonist
1) Confidence 0.45 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2265056 Disease Relevance 0.08 Pain Relevance 0.08
In the brain, TCDD exposure during the perinatal period may affect XRE-regulated gene expression through AhR activation and disrupt the differentiation of neurons, which are strictly regulated for developing brain formation

Conclusion

Regulation (regulated) of Gene_expression (activation) of AhR in brain
2) Confidence 0.43 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.16 Pain Relevance 0
In the brain, TCDD exposure during the perinatal period may affect XRE-regulated gene expression through AhR activation and disrupt the differentiation of neurons, which are strictly regulated for developing brain formation

Conclusion

Regulation (through) of Gene_expression (activation) of AhR in brain
3) Confidence 0.43 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.16 Pain Relevance 0
On the other hand boosting AhR expression via ?
Regulation (boosting) of Gene_expression (expression) of AhR
4) Confidence 0.40 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816705 Disease Relevance 0.59 Pain Relevance 0.04
AhR, CYP1A1 and cdc42 mRNA expression were quantified in AhR by real-time PCR.
Regulation (quantified) of Gene_expression (expression) of AhR
5) Confidence 0.38 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0 Pain Relevance 0

General Comments

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