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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.68
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pth1r) plasma membrane (Pth1r) nucleus (Pth1r)
intracellular (Pth1r) cytoplasm (Pth1r) signal transducer activity (Pth1r)
Anatomy Link Frequency
neurons 4
Pth1r (Mus musculus)
Pain Link Frequency Relevance Heat
vagus nerve 276 100.00 Very High Very High Very High
depression 38 77.64 Quite High
addiction 18 5.00 Very Low Very Low Very Low
Action potential 16 5.00 Very Low Very Low Very Low
medulla 12 5.00 Very Low Very Low Very Low
isoflurane 8 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
primary afferent fibers 6 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 99.88 Very High Very High Very High
Cancer 10 97.84 Very High Very High Very High
Chondroma 41 97.76 Very High Very High Very High
Enchondromatosis 56 95.80 Very High Very High Very High
Cleidocranial Dysplasia 2 80.16 Quite High
Depression 38 77.64 Quite High
Chondrosarcoma 12 41.36 Quite Low
Disseminated Intravascular Coagulation 10 36.76 Quite Low
Malignant Neoplastic Disease 14 34.32 Quite Low
Congenital Anomalies 6 27.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with this conclusion, transgenic mice expressing the mutant PTHR1 under the control of the collagen type II promoter develop tumors that are similar to those observed in human enchondromatosis.
Regulation (under) of Gene_expression (expressing) of mutant PTHR1 associated with targeted disruption, cancer and enchondromatosis
1) Confidence 0.23 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1592482 Disease Relevance 1.26 Pain Relevance 0
We classified DMX neurons in two groups because: i) these two Gaussian distributions showed the smallest overlap at a PPR value around 0.6; ii) there was a trough at around 0.6 for the distribution of PPR among DMX neurons; iii) the PPR of dm-cNTS neurons never exceeded 0.6.
Regulation (trough) of Gene_expression (distribution) of PPR in neurons associated with vagus nerve
2) Confidence 0.08 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2978217 Disease Relevance 0.21 Pain Relevance 0.70
We classified DMX neurons in two groups because: i) these two Gaussian distributions showed the smallest overlap at a PPR value around 0.6; ii) there was a trough at around 0.6 for the distribution of PPR among DMX neurons; iii) the PPR of dm-cNTS neurons never exceeded 0.6.
Regulation (trough) of Gene_expression (distribution) of PPR in neurons associated with vagus nerve
3) Confidence 0.08 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2978217 Disease Relevance 0.21 Pain Relevance 0.69

General Comments

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