INT198001

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Context Info
Confidence 0.26
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (MCL1) nucleoplasm (MCL1) cytosol (PIK3CA)
mitochondrion (MCL1) signal transduction (PIK3CA) nucleus (MCL1)
PIK3CA (Homo sapiens)
MCL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 2 42.72 Quite Low
Disease Link Frequency Relevance Heat
Apoptosis 108 98.20 Very High Very High Very High
Carcinoma 94 90.12 High High
Hepatocellular Cancer 9 50.00 Quite Low
Cancer 21 25.44 Quite Low
Leukemia 4 19.80 Low Low
Death 7 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Multiple Myeloma 3 5.00 Very Low Very Low Very Low
Lung Cancer 3 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have already shown that inhibition of PI3 kinase reduced expression of Mcl-1 in Hep3B cells and sensitized cells towards apoptosis induction by bleomycin [27].
Negative_regulation (inhibition) of PI3 kinase Negative_regulation (reduced) of Gene_expression (expression) of Mcl-1 associated with apoptosis
1) Confidence 0.26 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1601962 Disease Relevance 0.89 Pain Relevance 0

General Comments

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