INT198600

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.25
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CFH) extracellular region (CFH)
Anatomy Link Frequency
adipose tissue 4
CFH (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 3 85.28 High High
tolerance 34 73.84 Quite High
Inflammation 19 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
drug abuse 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 126 100.00 Very High Very High Very High
Myocardial Infarction 100 100.00 Very High Very High Very High
Insulin Resistance 46 99.76 Very High Very High Very High
Disorder Of Lipid Metabolism 18 99.72 Very High Very High Very High
Angina 1 85.28 High High
Impaired Glucose Tolerance 38 73.84 Quite High
Diabetes Mellitus 32 65.96 Quite High
Weight Loss 34 59.28 Quite High
Hemolytic Uremic Syndrome 14 50.00 Quite Low
Hyperinsulinism 4 35.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CFB gene expression in omental adipose tissue was positively associated with BMI, fasting glucose, and log fasting triglycerides and negatively with HDL cholesterol; CFH gene expression in omental adipose tissue was associated with insulin resistance (Table 3).
Negative_regulation (associated) of Gene_expression (expression) of CFH in adipose tissue associated with obesity, insulin resistance and disorder of lipid metabolism
1) Confidence 0.41 Published 2010 Journal Diabetes Section Body Doc Link PMC2797922 Disease Relevance 1.04 Pain Relevance 0
CFH gene expression has been reported in mice adipose tissue and nondifferentiated adipocytes but not in association with obesity or insulin resistance (37).
Negative_regulation (reported) of Gene_expression (expression) of CFH in adipose tissue associated with obesity and insulin resistance
2) Confidence 0.41 Published 2010 Journal Diabetes Section Body Doc Link PMC2797922 Disease Relevance 1.32 Pain Relevance 0.04
CFH dosage quotients showed an apparent heterozygous “deletion” of CFH exons 22 and 23 in II:8 (unaffected carrier), III:3 (unaffected carrier), III:6 (affected), and IV:1 (affected).
Negative_regulation (deletion) of Gene_expression (exons) of CFH
3) Confidence 0.37 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1626556 Disease Relevance 0 Pain Relevance 0
The HF group presented impaired LV function and low EF (EF ?
Negative_regulation (presented) of Gene_expression (group) of HF associated with myocardial infarction
4) Confidence 0.14 Published 2010 Journal BMC Syst Biol Section Body Doc Link PMC2890499 Disease Relevance 0.90 Pain Relevance 0.09

General Comments

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