INT198639

Context Info Confidence 0.15 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.49 Pain Relevance 0.04

extracellular region (S100A12, TNF) intracellular (TNF) extracellular matrix organization (TNF) cytoplasm (S100A12) cytosol (S100A12) extracellular space (TNF)

S100A12 (Homo sapiens) TNF (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 142 70.72 cytokine 149 50.00 Inflammatory response 10 5.00 corticosteroid 2 5.00 depression 2 5.00 addiction 2 5.00 Central nervous system 1 5.00 Inflammatory marker 1 5.00 Inflammatory mediators 1 5.00 monoamine 1 5.00

Disease Link Frequency Relevance Heat Malaria 210 98.68 Epilepsy 1 95.04 Communicable Diseases 22 92.00 Convulsion 10 89.32 Cerebral Malaria 24 86.92 Sepsis 75 84.80 Encephalopathy 27 78.92 Syndrome 7 76.52 INFLAMMATION 154 70.72 Disease 97 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

S100A12 is an IL-1 and TNF-inducible mediator found to be increased in severe malaria serum (M.

S100A12 Positive_regulation (mediator) of TNF-inducible associated with malaria

1) Confidence 0.15 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 1.49 Pain Relevance 0.04

General Comments

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