INT199780

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

immune system process (Ahr) cell morphogenesis (Ahr) DNA binding (Ahr)
response to stress (Ahr) cytoplasm (Ahr) signal transducer activity (Ahr)
Anatomy Link Frequency
lung 2
Ahr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 78.80 Quite High
Nicotine 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 68 92.64 High High
Prostate Cancer 56 91.24 High High
INFLAMMATION 6 78.80 Quite High
Frailty 6 78.24 Quite High
Stress 4 77.24 Quite High
Cancer 36 58.08 Quite High
Lung Cancer 6 21.92 Low Low
Disease Progression 1 7.36 Low Low
Malignant Neoplastic Disease 5 5.20 Low Low
Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin along with the upregulation of AhR (Figure 5D), it is possible that the cause of AhR elevation following ?
Spec (possible) Positive_regulation (elevation) of Localization (cause) of AhR
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816705 Disease Relevance 0.80 Pain Relevance 0.07
Although we did not observe changes of the AHR at the gene expression level, Martey et al. (2005) recently reported that cigarette smoke extract led to an activation of the AHR in cultured human lung fibroblasts based on induced nuclear translocation of the AHR (Martey et al. 2005).
Positive_regulation (induced) of Localization (translocation) of AHR in lung
2) Confidence 0.28 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1665420 Disease Relevance 0.23 Pain Relevance 0

General Comments

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