INT200463

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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 3.46
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SERPINB6) protein complex (SERPINB6) cytoplasm (SERPINB6)
Anatomy Link Frequency
body 1
SERPINB6 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 18 99.92 Very High Very High Very High
Pain score 16 98.52 Very High Very High Very High
Pain 168 97.96 Very High Very High Very High
nociceptor 16 93.68 High High
rheumatoid arthritis 24 51.24 Quite High
cva 26 40.16 Quite Low
Glutamate 108 5.00 Very Low Very Low Very Low
Inflammation 16 5.00 Very Low Very Low Very Low
spinal inflammation 16 5.00 Very Low Very Low Very Low
tolerance 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 16 99.92 Very High Very High Very High
Metatarsalgia 216 98.60 Very High Very High Very High
Pain 176 98.24 Very High Very High Very High
Obesity 32 97.00 Very High Very High Very High
Parkinson's Disease 2 86.72 High High
Peripheral Arterial Disease 24 75.00 Quite High
Hallux Valgus 24 58.84 Quite High
Hammer Toe Syndrome 32 58.08 Quite High
Foot Deformities 24 57.36 Quite High
Rheumatoid Arthritis 32 51.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, the absolute values of the MPP and PTI are not correlated to the treatment results.
Regulation (values) of PTI
1) Confidence 0.25 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1712337 Disease Relevance 0.41 Pain Relevance 0.07
Readjustment of MP placements for those who failed to demonstrate a decline in the PTI and MPP values after treatment should be considered to improve treatment results.
Regulation (values) of PTI
2) Confidence 0.22 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1712337 Disease Relevance 0.39 Pain Relevance 0
We found that the decline in the PTI and MPP values after MP application was correlated to subjective pain improvement.
Regulation (values) of PTI associated with pain
3) Confidence 0.22 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1712337 Disease Relevance 0.47 Pain Relevance 0.10
We found that the MPP and PTI values before and after treatment did not correlate to the subjective outcome rating or pain improvement.
Regulation (values) of PTI associated with pain
4) Confidence 0.22 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1712337 Disease Relevance 0.50 Pain Relevance 0.54
The pre- and post-treatment MPP and PTI values or the DS in the MPP position in the matrix were not statistically correlated to changes in the VAS (Table 4).


Regulation (values) of PTI
5) Confidence 0.22 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1712337 Disease Relevance 0 Pain Relevance 0
Declines in the PTI and MPP values after MP application were statistically correlated with the improvement in VAS scores (r = 0.77, R2 = 0.59, p < 0.001; r = 0.60, R2 = 0.36, p = 0.009).


Regulation (values) of PTI
6) Confidence 0.22 Published 2006 Journal BMC Musculoskelet Disord Section Abstract Doc Link PMC1712337 Disease Relevance 0.49 Pain Relevance 0.15
Declines in the PTI and MPP values after MP placement significantly correlated to the decrease in the VAS scores (r = 0.77, R2 = 0.59, p < 0.001; r = 0.60, R2 = 0.36, p < 0.009) (Figure 2).
Regulation (values) of PTI
7) Confidence 0.22 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1712337 Disease Relevance 0 Pain Relevance 0
However, neither the pre-treatment values of the MPP and PTI shift in the position of the MPP after treatment, nor the age, gender and body mass index (BMI) of the subjects were statistically correlated with subjective improvement.
Regulation (values) of PTI in body associated with obesity
8) Confidence 0.10 Published 2006 Journal BMC Musculoskelet Disord Section Abstract Doc Link PMC1712337 Disease Relevance 0.67 Pain Relevance 0.22
Further studies are required to determine if relative changes in ptiO2 reflecting alterations in microcirculatory perfusion unmask relative ischemia at ptiO2 values above the ischemic threshold of 10 mmHg.
Spec (determine) Regulation (changes) of ptiO2 associated with ischemia
9) Confidence 0.00 Published 2010 Journal Crit Care Section Body Doc Link PMC2875528 Disease Relevance 0.29 Pain Relevance 0.10
Further studies are required to determine if relative changes in ptiO2 reflecting alterations in microcirculatory perfusion unmask relative ischemia at ptiO2 values above the ischemic threshold of 10 mmHg.
Regulation (values) of ptiO2 associated with ischemia
10) Confidence 0.00 Published 2010 Journal Crit Care Section Body Doc Link PMC2875528 Disease Relevance 0.23 Pain Relevance 0.08

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