INT200581

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP) cell-cell signaling (AVP) response to stress (AVP)
signal transducer activity (AVP) cytosol (AVP) extracellular space (AVP)
AVP (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endotoxemia 9 98.92 Very High Very High Very High
Sepsis 15 88.72 High High
Depression 1 83.40 Quite High
Stroke 5 76.40 Quite High
Increased Venous Pressure Under Development 4 49.64 Quite Low
Hypotension 7 18.84 Low Low
Death 3 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 3 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Key messages

• AVP impairs the CI and the systemic oxygen supply when used in a moderate dose (0.04 U min-1) in ovine endotoxemia. • In fluid-challenged endotoxemic sheep, dobutamine reverses the AVP-associated impairment in CI, DO2I and SvO2, and further increases MAP. • The dobutamine-associated effects are dose-dependent and strongest at an infusion rate of 10 ?

Negative_regulation (reverses) of Negative_regulation (impairment) of AVP-associated associated with endotoxemia
1) Confidence 0.41 Published 2006 Journal Crit Care Section Body Doc Link PMC1751059 Disease Relevance 0.46 Pain Relevance 0

General Comments

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