INT200816

Context Info Confidence 0.19 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.51 Pain Relevance 0.03

cytosol (Jak2, Mvd) kinase activity (Jak2, Mvd) cell differentiation (Jak2) lyase activity (Mvd) histone binding (Jak2) peroxisome (Mvd)

Jak2 (Mus musculus) Mvd (Mus musculus) Jak2 - V617F (1)

Pain Link Frequency Relevance Heat cva 1 53.92 cytokine 3 5.00 fibrosis 3 5.00 Parenteral administration 2 5.00 anesthesia 1 5.00 isoflurane 1 5.00 Bioavailability 1 5.00

Disease Link Frequency Relevance Heat Myelodysplastic Syndromes 62 99.36 Erythrocytosis 35 98.40 Congenital Anomalies 10 96.36 Sprains And Strains 13 93.12 Thrombosis Related Under Development 5 91.76 Hemorrhage 10 89.96 Myeloid Leukemia 9 86.64 Leukocytosis 6 77.84 Splenomegaly 3 72.56 Hyperplasia 1 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Pathological characterization of MPD induced by JAK2 V617F

JAK2 V617F (V617F) Positive_regulation (induced) of MPD Binding (characterization) of

1) Confidence 0.19 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762384 Disease Relevance 1.51 Pain Relevance 0.03

General Comments

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