INT20201

From wiki-pain
Revision as of 10:58, 24 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 1990
Last Reported 2009
Negated 0
Speculated 2
Reported most in Body
Documents 8
Total Number 11
Disease Relevance 15.13
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fgf12)
Anatomy Link Frequency
liver 2
Fgf12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 35 100.00 Very High Very High Very High
withdrawal 1 94.48 High High
alcohol 4 57.80 Quite High
fibrosis 1 55.04 Quite High
carbamazepine 3 41.92 Quite Low
halothane 3 40.16 Quite Low
Inflammation 21 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Liver Failure 372 100.00 Very High Very High Very High
Hepatotoxicity 2 100.00 Very High Very High Very High
Hepatitis 82 99.80 Very High Very High Very High
Hepatitis Virus Infection 16 99.72 Very High Very High Very High
Toxicity 16 99.68 Very High Very High Very High
Hepatitis A Virus Infection 13 99.04 Very High Very High Very High
Lymphatic System Cancer 18 98.48 Very High Very High Very High
Hepatitis B Virus Infection 21 97.48 Very High Very High Very High
Sepsis 6 97.36 Very High Very High Very High
Disease 13 96.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cause of FHF was hepatitis A virus (HAV) in 4 patients, hepatitis B virus (HBV) in 7, paracetamol overdose in 5, ecstasy in 2, hepatotoxic drugs in 4, autoimmune hepatitis in 2, liver lesions of preeclampsia in 1 and unknown in 5.
Positive_regulation (cause) of FHF in liver associated with paracetamol, hepatitis a virus infection, pre-eclampsia, autoimmune hepatitis, acute liver failure, hepatitis b virus infection, hepatitis and overdose
1) Confidence 0.43 Published 1996 Journal Hepatology Section Abstract Doc Link 8621143 Disease Relevance 1.23 Pain Relevance 0.17
Interestingly, in NHL, chemotherapy induced FHF has also been described in the literature, however in our case no such history was detected.
Positive_regulation (induced) of FHF associated with acute liver failure
2) Confidence 0.39 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1971252 Disease Relevance 1.37 Pain Relevance 0
In this review, we examine the specific causes of FHF, including acetaminophen-related hepatotoxicity, drug- and viral-related FHF, and other less common causes of FHF such as pregnancy and vascular related disease.
Spec (examine) Positive_regulation (causes) of FHF associated with paracetamol, hepatotoxicity and disease
3) Confidence 0.38 Published 2003 Journal Semin. Gastrointest. Dis. Section Abstract Doc Link 12889583 Disease Relevance 0.99 Pain Relevance 0.10
In this review, we examine the specific causes of FHF, including acetaminophen-related hepatotoxicity, drug- and viral-related FHF, and other less common causes of FHF such as pregnancy and vascular related disease.
Spec (examine) Positive_regulation (causes) of FHF associated with paracetamol, hepatotoxicity and disease
4) Confidence 0.33 Published 2003 Journal Semin. Gastrointest. Dis. Section Abstract Doc Link 12889583 Disease Relevance 1.00 Pain Relevance 0.10
In United States some investigators documented viral hepatitis as the leading cause of FHF (in one eighth of total FHF cases) followed by drug toxicity and idiosyncrasy, while other investigators found acetaminophen toxicity followed by non A non B non C hepatitis as the leading cause of FHF [7-9].
Positive_regulation (cause) of FHF associated with toxicity, paracetamol, acute liver failure, hepatitis virus infection and hepatitis
5) Confidence 0.28 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1971252 Disease Relevance 2.26 Pain Relevance 0.10
The etiology of FHF is multifactorial, including viral hepatitis and drug toxicity [7], as can be seen in the present study where viral hepatitis is the major cause of FHF (79.5% of total known etiologies).
Positive_regulation (cause) of FHF associated with toxicity, hepatitis virus infection and acute liver failure
6) Confidence 0.26 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1971252 Disease Relevance 2.18 Pain Relevance 0
Most frequent causes of FHF were hepatitis B virus and drug-related (not acetaminophen) liver failure.
Positive_regulation (causes) of FHF in liver
7) Confidence 0.10 Published 2007 Journal World J. Gastroenterol. Section Body Doc Link 17457975 Disease Relevance 0.10 Pain Relevance 0
Although paracetamol toxicity is the leading cause of FHF in Western countries, being responsible for 39% of the cases in USA,[13] 73% in UK,[15] and 70% in Denmark,[16] FHF in developing countries is predominantly due to the various hepatitis viruses.
Positive_regulation (cause) of FHF associated with toxicity, paracetamol, acute liver failure and hepatitis
8) Confidence 0.02 Published 2009 Journal Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association Section Body Doc Link PMC2981838 Disease Relevance 2.17 Pain Relevance 0.18
In our series, HEV hepatitis is the commonest cause of FHF.
Positive_regulation (cause) of FHF associated with acute liver failure and hepatitis
9) Confidence 0.02 Published 2009 Journal Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association Section Body Doc Link PMC2981838 Disease Relevance 2.13 Pain Relevance 0.19
These results confirm that the coagulation system is activated in FHF.
Positive_regulation (activated) of FHF associated with acute liver failure
10) Confidence 0.01 Published 1990 Journal Eur. J. Clin. Invest. Section Abstract Doc Link 2127751 Disease Relevance 0.75 Pain Relevance 0.07
TAT was significantly increased in patients with FHF compared with control subjects (25.8 +/- 2.7 micrograms l-1) compared with 2.6 +/- 0.2 micrograms l-1; n = 10: P less than 0.001).
Positive_regulation (increased) of FHF associated with acute liver failure
11) Confidence 0.01 Published 1990 Journal Eur. J. Clin. Invest. Section Abstract Doc Link 2127751 Disease Relevance 0.97 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox