INT202043

From wiki-pain
Revision as of 18:13, 20 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MMP13, COL2A1) extracellular region (MMP13, COL2A1) peptidase activity (MMP13)
Golgi apparatus (MMP13) proteinaceous extracellular matrix (MMP13) cytoplasm (COL2A1)
Anatomy Link Frequency
cleavage 2
MMP13 (Homo sapiens)
COL2A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 60 100.00 Very High Very High Very High
rheumatoid arthritis 16 96.80 Very High Very High Very High
Inflammation 18 95.24 Very High Very High Very High
Arthritis 39 74.24 Quite High
Osteoarthritis 18 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 16 96.80 Very High Very High Very High
INFLAMMATION 13 95.24 Very High Very High Very High
Arthritis 44 75.28 Quite High
Disease 8 69.32 Quite High
Juvenile Chronic Polyarthritis 1 64.40 Quite High
Disease Progression 1 25.20 Quite Low
Osteoarthritis 19 5.00 Very Low Very Low Very Low
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low
Ankylosing Spondylitis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since we found that MMP-2 is mostly found in its proform in SF, our results favour the implication of MMP-13 Interestingly, MMP-13, which is responsible for cleavage of type II collagen [36,37], aggrecan [38], and fibrinogen [39], has been shown to be increased in RA SF [3] and to be linked to synovial inflammation and bone destruction [40].
MMP-13 Regulation (responsible) of Protein_catabolism (cleavage) of type II collagen in cleavage associated with inflammation, rheumatoid arthritis and metalloproteinase
1) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779417 Disease Relevance 0.54 Pain Relevance 0.54

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox