INT202219

Context Info Confidence 0.36 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.03

signal transduction (Nmur1) plasma membrane (Nmur1) signal transducer activity (Nmur1)

Anatomy Link Frequency neuronal 1 Nmur1 (Mus musculus)

Pain Link Frequency Relevance Heat addiction 2 69.44 Mechanotransduction 5 36.64 qutenza 4 6.88 withdrawal 10 5.00 Action potential 6 5.00 Pain 3 5.00 Mechanosensation 2 5.00 antagonist 2 5.00 Nerve growth factor 1 5.00 ASIC 1 5.00

Disease Link Frequency Relevance Heat Rheumatoid Arthritis 5 29.60 Pain 4 5.00 Nociception 1 5.00 Stress 1 5.00 Ganglion Cysts 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

M FM3-25 (which also binds cell membranes) no significant labelling of the neuronal cytoplasm was observed (Figs. 2c,d), suggesting that the molecule cannot permeate the channel and that FM1-43 uptake is not via non-specific membrane binding.

FM3 Binding (binds) of in neuronal

1) Confidence 0.36 Published 2007 Journal Mol Pain Section Body Doc Link PMC1779769 Disease Relevance 0 Pain Relevance 0.03

General Comments

This test has worked.