INT202307

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.24
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PDGFB) cytoplasm (PDGFB)
PDGFB (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 81 91.92 High High
isoflurane 3 88.64 High High
anesthesia 3 87.76 High High
antagonist 2 68.96 Quite High
Inflammation 15 56.84 Quite High
cytokine 15 48.24 Quite Low
Glutamate 6 48.16 Quite Low
fibrosis 17 13.00 Low Low
ischemia 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 9 99.96 Very High Very High Very High
Brain Tumor 4 99.12 Very High Very High Very High
Wound Healing 6 96.80 Very High Very High Very High
Gliosis 1 85.60 High High
Glioblastoma 2 77.28 Quite High
Cancer 45 75.56 Quite High
Hyperplasia 2 69.64 Quite High
INFLAMMATION 17 56.84 Quite High
Neuroblastoma 1 41.36 Quite Low
Meningioma 1 21.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to investigate the effect of PDGF release rate on PDGF biological function in vivo, nine groups of 3 animals each were prepared to test in a rat wound healing model. [24] They were grouped as follows:
Spec (investigate) Regulation (effect) of Spec (investigate) Gene_expression (biological) of PDGF associated with wound healing
1) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0.10 Pain Relevance 0.13
Thus, the controlled delivery of PDGF will likely be critical for clinical success.[36]
Regulation (controlled) of Gene_expression (delivery) of PDGF
2) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0.06 Pain Relevance 0.27
Thus, the controlled delivery of PDGF will likely be critical for clinical success.[36]
Regulation (critical) of Gene_expression (delivery) of PDGF
3) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0.06 Pain Relevance 0.27
In gliomas, analysis of PDGF/PDGFR expression suggested the presence of autocrine and paracrine loops of PDGF in glioma activating PDGFR-?
Regulation (analysis) of Gene_expression (expression) of PDGF associated with glioma
4) Confidence 0.24 Published 2007 Journal Radiat Oncol Section Body Doc Link PMC1780053 Disease Relevance 1.03 Pain Relevance 0.03

General Comments

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