INT202819

Context Info Confidence 0.00 First Reported 2007 Last Reported 2007 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.74 Pain Relevance 0.03

isomerase activity (Dse) Golgi apparatus (Dse) endoplasmic reticulum (Dse)

Dse (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 12 66.96 headache 5 5.00 depression 2 5.00 Paracetamol 2 5.00 Central nervous system 1 5.00 tramadol 1 5.00 Multiple sclerosis 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Muscle Disease 58 98.32 Distal Myopathy 1 94.28 INFLAMMATION 11 66.96 Disease 3 60.76 Muscle Weakness 1 51.20 Adhesions 3 46.64 Muscular Dystrophy 2 24.56 Walker-warburg Syndrome 1 21.44 Brain Disease 1 19.12 Vomiting 7 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

HIBM-associated GNE mutations, whether in the epimerase or the kinase domain, result in reduced activity of both UDP-GlcNAc 2-epimerase and ManNAc kinase [16,17].

Spec (whether) Negative_regulation (reduced) of epimerase associated with muscle disease

1) Confidence 0.00 Published 2007 Journal BMC Neurol Section Body Doc Link PMC1790898 Disease Relevance 0.74 Pain Relevance 0.03

General Comments

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