INT202930

Context Info Confidence 0.01 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.45 Pain Relevance 0.05

extracellular space (LAMB1, Fbln5) extracellular region (LAMB1, Fbln5) cell adhesion (LAMB1, Fbln5) structural molecule activity (LAMB1) extracellular matrix organization (Fbln5) enzyme binding (LAMB1)

Anatomy Link Frequency aorta 1 LAMB1 (Homo sapiens) Fbln5 (Mus musculus)

Pain Link Frequency Relevance Heat cva 2 90.28 amygdala 1 43.20 ketamine 2 5.00 anesthesia 2 5.00 Hippocampus 1 5.00

Disease Link Frequency Relevance Heat Cutis Laxa 2 100.00 Hemorrhage 2 90.28 Targeted Disruption 7 88.12 Aneurism 5 82.56 Stress 1 46.24 Anxiety Disorder 1 31.36 Disease 6 5.00 Sprains And Strains 3 5.00 Alzheimer's Dementia 1 5.00 Obesity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Homozygous mutation in fibulin-5 is associated with a form of recessive cutis laxa, recognized in humans by sagging skin and a tortuous aorta.

cutis laxa Binding (recognized) of fibulin-5 in aorta associated with cutis laxa

1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1794134 Disease Relevance 0.45 Pain Relevance 0.05

General Comments

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