INT203133

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 6.17
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
macrophages 5
dendritic cells 1
Neutrophils 1
Cxam (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 147 99.40 Very High Very High Very High
Arthritis 174 96.40 Very High Very High Very High
rheumatoid arthritis 62 79.40 Quite High
cytokine 54 76.24 Quite High
Inflammatory response 18 71.64 Quite High
chemokine 10 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 166 99.86 Very High Very High Very High
INFLAMMATION 172 99.40 Very High Very High Very High
Necrosis 21 98.76 Very High Very High Very High
Gastritis 5 97.00 Very High Very High Very High
Arthritis 182 96.40 Very High Very High Very High
Stomach Cancer 110 94.72 High High
Targeted Disruption 34 91.12 High High
Intestinal Polyposis 15 88.72 High High
Disease 94 80.88 Quite High
Polyps 25 80.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neutrophils and macrophages are important inflammatory cells and the secretion of tumour necrosis factor-?
Gene_expression (Neutrophils) of macrophages in Neutrophils associated with necrosis, inflammation and cancer
1) Confidence 0.07 Published 2006 Journal Arthritis Res Ther Section Abstract Doc Link PMC1794524 Disease Relevance 1.26 Pain Relevance 0.46
Activated macrophages promote Wnt signalling through tumour necrosis factor-?
Gene_expression (promote) of macrophages in macrophages associated with necrosis and cancer
2) Confidence 0.04 Published 2008 Journal EMBO J Section Title Doc Link PMC2413189 Disease Relevance 0.61 Pain Relevance 0
Therefore, it is also possible that activated macrophages suppress ?
Gene_expression (suppress) of macrophages in macrophages
3) Confidence 0.04 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.52 Pain Relevance 0.03
Because the activation of PGE2 signalling induces infiltration and activation of macrophages in the gastric mucosa (Oshima et al, 2004, 2005), these results collectively suggest that activated macrophages promote the Wnt/?
Gene_expression (promote) of macrophages in macrophages
4) Confidence 0.04 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 1.34 Pain Relevance 0.10
-expressing cells in gastric tumours to be macrophages, whereas CD11c-positive dendritic cells were rarely detected (Supplementary Figure 6A).
Gene_expression (detected) of macrophages in dendritic cells associated with cancer
5) Confidence 0.04 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.49 Pain Relevance 0.14
However, mucosal macrophages were still found in the stomach of the K19-C2mE op/op compound mice (Supplementary Figure 1).
Gene_expression (found) of macrophages in macrophages
6) Confidence 0.04 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.67 Pain Relevance 0.04
Neutrophils and macrophages are important inflammatory cells and the secretion of tumour necrosis factor-?
Gene_expression (Neutrophils) of macrophages in macrophages associated with necrosis, inflammation and cancer
7) Confidence 0.02 Published 2006 Journal Arthritis Res Ther Section Abstract Doc Link PMC1794524 Disease Relevance 1.26 Pain Relevance 0.46

General Comments

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