INT203852

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(Generated page)
 
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|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
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fontcolor=white,
 
fontcolor=white,
 
label="Binding",
 
label="Binding",
−
URL=Binding
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Binding"
 
];
 
];
 
node2
 
node2
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fontcolor=white,
 
fontcolor=white,
 
label="Eif2ak2",
 
label="Eif2ak2",
−
URL="Eif2ak2"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:19106"
 
];
 
];
 
node3
 
node3
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fontcolor=white,
 
fontcolor=white,
 
label="Lna1",
 
label="Lna1",
−
URL="Lna1"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:104188"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
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{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[RNA binding]] ([[Eif2ak2]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:RNA binding|RNA binding]] ([[G:19106|Eif2ak2]])
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[nucleus]] ([[Eif2ak2]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:nucleus|nucleus]] ([[G:19106|Eif2ak2]])
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[intracellular]] ([[Eif2ak2]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:intracellular|intracellular]] ([[G:19106|Eif2ak2]])
 
|-
 
|-
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[translation]] ([[Eif2ak2]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:translation|translation]] ([[G:19106|Eif2ak2]])
−
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[kinase activity]] ([[Eif2ak2]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:kinase activity|kinase activity]] ([[G:19106|Eif2ak2]])
 
|-
 
|-
 
|}
 
|}
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Potency]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Potency|Potency]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[anesthesia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:anesthesia|anesthesia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammation|Inflammation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[isoflurane]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:isoflurane|isoflurane]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
−
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Apoptosis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Apoptosis|Apoptosis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Stress]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Stress|Stress]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 84.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 84.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hepatotoxicity]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Hepatotoxicity|Hepatotoxicity]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 39
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 39
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Toxicity]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Toxicity|Toxicity]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 66.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 66.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Reprotox - General 1]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Body Weight|Body Weight]]
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Weight Loss]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Weight Loss|Weight Loss]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Body Weight]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Reprotox - General 1|Reprotox - General 1]]
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dislocations]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Injury|Injury]]
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Death]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Death|Death]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Necrosis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Rhinitis|Rhinitis]]
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
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{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
−
| <span style="color:#800000">'''PKR'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">interact</span>) of <span style="color:#800000">'''LNA'''</span>
+
|  [[G:19106|<span style="color:#800000">'''PKR'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">interact</span>) of [[G:104188|<span style="color:#800000">'''LNA'''</span>]]
 
|-
 
|-
 
|}
 
|}
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
−
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Nucleic Acids Research|Nucleic Acids Research]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Nucleic Acids Research|Nucleic Acids Research]]

Latest revision as of 08:50, 20 September 2012

Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Eif2ak2) nucleus (Eif2ak2) intracellular (Eif2ak2)
translation (Eif2ak2) kinase activity (Eif2ak2)
Eif2ak2 (Mus musculus)
Lna1 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 52 72.56 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 20 92.32 High High
Stress 2 84.32 Quite High
Hepatotoxicity 39 83.36 Quite High
Toxicity 28 66.96 Quite High
Body Weight 8 5.00 Very Low Very Low Very Low
Weight Loss 5 5.00 Very Low Very Low Very Low
Reprotox - General 1 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Rhinitis 2 5.00 Very Low Very Low Very Low

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It remains to be determined if LNA oligonucleotides interact with PKR, and more extensive mechanistic work is required to confirm both p-eIF2?
PKR Binding (interact) of LNA
1) Confidence 0.03 Published 2007 Journal Nucleic Acids Research Section Body Doc Link PMC1802611 Disease Relevance 0.65 Pain Relevance 0.10

[edit] General Comments

This test has worked.

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