INT203981

Context Info Confidence 0.40 First Reported 2007 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 6 Total Number 6 Disease Relevance 0.13 Pain Relevance 0.23

Anatomy Mention Frequency neuronal 2 ca2 (Danio rerio)

Pain Term Frequency Confidence Heat Eae 4 90.36 imagery 55 74.92 Glutamate 1 70.32 tetrodotoxin 16 60.88 Nicotine 22 54.80 addiction 3 50.00 lidocaine 2 46.24 Action potential 40 29.28 Spinal cord 1 5.00 member 8 3 5.00

Disease Term Frequency Confidence Heat Targeted Disruption 16 74.64 Hyperplasia 2 55.32 Toxicity 5 46.88 Hypoxia 1 5.00 Muscular Dystrophy 1 5.00 Central Core Disease 12 5.00 Hypercapnia 1 5.00 Malignant Hyperthermia 1 5.00 Injury 1 5.00 Renal Tubular Acidosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, we also noted that ectopic epidermal ICs occurred at the expense of the epidermal SC fate, since the epidermal SC marker of P63 was completely abolished in some regions where high levels of atp1b1b and ca2a were expressed (Figure 7E and 7F, highlighted by arrows).

Positive_regulation (levels) of Gene_expression (expressed) of ca2a

1) Confidence 0.40 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1810426 Disease Relevance 0 Pain Relevance 0

This strongly suggests that the secondary Ca2+ response in specific neuronal ensembles was identified because of the method employed, which involved continuous recording of Ca2+ signals over a long period and selection of time integrals from 50 milliseconds to 10?

Positive_regulation (secondary) of Gene_expression (response) of Ca2 in neuronal

2) Confidence 0.25 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1803028 Disease Relevance 0.13 Pain Relevance 0.17

Detection of Ca2+-induced bioluminescence activities

Positive_regulation (induced) of Gene_expression (Detection) of Ca2

3) Confidence 0.25 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1803028 Disease Relevance 0 Pain Relevance 0.03

Effects of environmental Ca2+ levels on ecac, pmca, and ncx mRNA expressions

Positive_regulation (environmental) of Gene_expression (levels) of Ca2

4) Confidence 0.15 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2140269 Disease Relevance 0 Pain Relevance 0

We observe that the preference for Ca2+ over K+ in the selectivity filter decreases to R?

Positive_regulation (preference) of Gene_expression (preference) of Ca2

5) Confidence 0.07 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2668181 Disease Relevance 0 Pain Relevance 0

One voltage-activated channel gene with high homology with both the invertebrate Na+ channel and vertebrate Na+ and Ca2+ channel ?

Positive_regulation (vertebrate) of Gene_expression (channel) of Ca2

6) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2654917 Disease Relevance 0 Pain Relevance 0.04

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