INT204106

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2009
Negated 2
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.16
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GEM) plasma membrane (GEM) GTPase activity (GEM)
Anatomy Link Frequency
AsPC-1 2
GEM (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 31 98.40 Very High Very High Very High
Inflammation 10 76.80 Quite High
palliative 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Infliximab 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 74 99.64 Very High Very High Very High
Disease 17 98.88 Very High Very High Very High
Rheumatoid Arthritis 32 98.40 Very High Very High Very High
Pancreatic Cancer 96 84.80 Quite High
Breast Cancer 2 81.36 Quite High
Autoimmune Disease 2 77.00 Quite High
INFLAMMATION 10 76.80 Quite High
Adhesions 14 59.08 Quite High
Increased Venous Pressure Under Development 1 50.24 Quite High
Cancer 34 31.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
whether KIR expression correlates with disease activity in
Spec (whether) Regulation (whether) of KIR associated with disease
1) Confidence 0.21 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC1804296 Disease Relevance 0.97 Pain Relevance 0.28
However, FRNK overexpression did not significantly affect Gem-induced apoptosis in AsPC-1 cells on plastic (Fig. 10B).
Neg (not) Regulation (affect) of Gem in AsPC-1 associated with apoptosis
2) Confidence 0.19 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.50 Pain Relevance 0
However, FRNK overexpression did not significantly affect Gem-induced apoptosis in AsPC-1 cells that had low level of pFAK (pY397).
Neg (not) Regulation (affect) of Gem in AsPC-1 associated with apoptosis
3) Confidence 0.19 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.69 Pain Relevance 0

General Comments

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